Wednesday, March 30, 2011

SLUG BAM: Muscarinic effects of Acetylcholine

Acetylcholine acts on two vastly different classes of receptors - nicotinic receptors (with two subtypes, one at the neuromuscular junction of skeletal muscle, the other within ganglia and the CNS), and muscarinic receptors (widely distributed within both peripheral and central nervous systems).

**Muscarinic effects SLUG BAM:
  • Salivation/ Secretions/ Sweating
  • Lacrimation
  • Urination
  • Gastrointestinal upset
  • Bradycardia/ Bronchoconstriction/ Bowel movement
  • Abdominal cramps/ Anorexia
  • Miosis

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