Solved paper of 4th year special pathology GIT

BOLD OPTIONS are correct answers q1.which is the most common site of metastasis of colorectal carcinoma ? a.bones b.liver c.regional lymph nodes d.kidney Q2.regarding colorectal carcinoma .which is the the most appropriate statement? a.carcinoma of proximal colon are annular lesions b.polypoid, exophytic masses are abundant in proximal colon cancer c.polypoid ,exophytic masses are abundant in distal colon cancer d.distal colon cancer rarely cause obstruction Q3.along with colorectal carcinoma ,familial adenomatous polyposis is also associated with which extraintestinal manifestation ? a.pulmonary eosinophilia b.pancreatic carcinoma c.hypertrophy of retinal pigment d.seborrhic keratitis Q4.A 70 year old man diagnosed with colorectal carcinoma ,after some days noticed some improvement using NSAID because? a.of its non-steroidal effect b.it causes inhibition of COX2 c.of its analgesic effect d.it causes production of PGE2 Q5.Mutation in the following gene causes colorectal carcinoma? a.APC/E catenin b.K-RAS /mismatch repair c.DNA mismatch repair d.APC/B (beta) catenin mismatch repair gene Q6.Appendicitis is caused due to obstruction caused by all of the following except : a.feacalith b.gallstone c.villous protrusion d.oxyuriaisis vermicularis Q7.the following feature characterizes acute appendicitis : a.neutrophilic infiltration of muscularis propria b.lymphocyte aggregates in appendical lumen c.antigen-antibody reaction against mucosal cells of appendix d.formation of villous projections Q8.which of the following diseases presents the symptoms like appendicitis making the diagnosis difficult ? a.peptic ulcer b.meckel's diverticulitis c.carcinoma of colon d.ruptured ovarian follicle at ovulation e.both 'b' and 'd' q9.select the correct statement about the tumors of appendix : a.cystadenomas are locally malignant tumors b.mucocele is a precancerous condition c.carcinoids are the least common tumors in appendix d.when peritoneal cavity fills with mucus from an invading cystadenocarcinoma ,it is pseudomyxoma peritoni Q10.choose the correct about morphology of appendicitis a.hemorrhagic green ulceration and green black gangrenous mucosa shows acute gangrenous appendicitis b.normal mucosa is turned bluish in case of appendicitis due to congestion c.no presence of ulceration and foci in accute suppurative appendicitis