SOLVED PAPER of third Year MBBS- BIOCHEMISTRY- "Mechanisms of action of hormones

Q1 Grave's disease is associated with which hormone a) Thyroid hormones b) Androgens c) Catecholamines d) Pituitary hormones e) None of them Q2 The normal daily intake of iodide is a) 200-600 µg b) 300-700 µg c) 100-200 µg d) 400-500 µg e) None of these Q3 Regarding T3 a) T3 appears to be major thyroid hormone metabollicaly b) Although the circulating levels of T3 are much lower than the corresponding T4 levels c) T3 is 3-5 times more active than T4 d) T3 is loosely bounded to serum proteins e) All of these Q4 Clinical features of hyperthyroidism include a) Goitre, heat intolerance, weight loss and tachycardia b) Goitre, tachycardia and cold intolerance c) Exophthalmos, goiter, tachycardia and loss of appetite d) Exophthalmos, goiter and obesity e) None of these Q5 All hormons increased the no of prolactin receptors on the mammary cell membranne,except a) Estrogen b) Thyroid hormone c) Glucocorticoides d) Progesterone e) None of these Q6 Vasopressin and oxytocin circulate unbound to proteins and have very short plasma half lives, on the order of a) 1-2 minutes b) 2-4 minutes c) 5-8 minutes d) 10-12 minutes Q7 Reverse T3 is a) A synthetic compound given counter the effectsof T3 b) Formed from T4 but has no hormone function c) Formed by isomerisation of T3 d) Formed from T4 and has hormone function e) All of them Q8 Activated phospholipase C acts on a) Phosphatidyl inositol-4, 5-biphosphate b) Inositol-1, 4, 5-triphosphate c) Protein kinase C d) Pl-3 kinase e) none of these Q9 Which of the following does not act via adenylyl cylcase pathway a) GHRH b) CRH c) Prolactin d) Erythropietin e) Both C and D Q10 Tissue level of cyclic AMP can be influenced by a) Hormones b) Nicotinic acid c) Imidazole d) Methyl xanthine e) All of them